Januvia (Sitagliptin) 50mg Tablets

Januvia (Sitagliptin) 50mg Tablets

$519.00$1,422.00

Januvia (Sitagliptin) 50mg Tablets is a prescription medication for type 2 diabetes mellitus. It belongs to a class of drugs known as DPP-4 inhibitors (dipeptidyl peptidase-4 inhibitors). Januvia works by helping control blood sugar levels in individuals with type 2 diabetes. The active ingredient, sitagliptin, helps regulate the amount of insulin your body produces after eating and decreases the amount of glucose (sugar) your liver produces.

Sitagliptin is not for use in type 1 diabetes or diabetic ketoacidosis, a severe complication of diabetes. Januvia is typically prescribed alongside diet and exercise to help improve blood sugar control, but it is not a substitute for insulin.

Active Ingredient

Januvia’s active ingredient is sitagliptin, a selective inhibitor of the enzyme DPP-4 (dipeptidyl peptidase-4). DPP-4 plays a role in breaking down incretin hormones that help regulate blood sugar levels. Incretins stimulate the pancreas to release insulin and reduce the liver’s glucose production after meals. By inhibiting DPP-4, sitagliptin helps to increase the levels of these incretin hormones, which in turn helps improve blood sugar control.

Sitagliptin is available in various dosages, and the 50mg tablet is a commonly prescribed strength for patients who need moderate control of their blood sugar levels.

Thumbnail Select Quantity (Tablets) PriceQuantity
Januvia (Sitagliptin) 50mg Tablets - 30 Tablets 30 Tablets $519.00
Januvia (Sitagliptin) 50mg Tablets - 60 Tablets 60 Tablets $966.00
Januvia (Sitagliptin) 50mg Tablets - 90 Tablets 90 Tablets $1,422.00

How It Works

Januvia works by inhibiting DPP-4, an enzyme that breaks down incretin hormones like GLP-1 (glucagon-like peptide-1) and GIP (gastric inhibitory polypeptide). These hormones help regulate insulin secretion from the pancreas in response to meals. In people with type 2 diabetes, these incretin hormones may be less effective, leading to higher blood sugar levels.

By blocking the action of DPP-4, Januvia increases the levels of active incretins, which help:

  1. Increase Insulin Release: The pancreas releases more insulin in response to meals, helping lower blood sugar.
  2. Reduce Glucose Production by the Liver: Januvia also helps lower the amount of glucose the liver releases into the bloodstream, further helping to control blood sugar.
  3. Decrease Blood Sugar: By improving insulin sensitivity and reducing the liver’s glucose output, Januvia helps lower blood sugar levels, particularly after meals.

Uses

Januvia is primarily used to treat type 2 diabetes, a condition where the body either doesn’t make enough insulin or doesn’t respond appropriately to insulin. It is used as part of a comprehensive treatment plan that includes:

  1. Dietary Modifications: A proper diet that helps maintain a healthy weight and supports blood sugar control.
  2. Exercise: Physical activity that helps improve insulin sensitivity and blood sugar management.
  3. Other Medications: Januvia is often used in combination with other oral diabetes medications, such as metformin or sulfonylureas, or with insulin therapy, depending on individual needs.

Januvia may help improve blood sugar control in people with type 2 diabetes, but it is not a cure. To manage the condition effectively, it is important to continue monitoring blood sugar levels regularly, follow your healthcare provider’s instructions, and make lifestyle changes.

Benefits

  1. Improves Blood Sugar Control: Januvia effectively lowers fasting blood glucose levels and postprandial (after-meal) blood sugar levels in people with type 2 diabetes.
  2. No Weight Gain: Unlike some other diabetes medications, Januvia does not typically cause weight gain. In fact, some people may even lose a small amount of weight while taking it.
  3. Minimal Risk of Low Blood Sugar (Hypoglycemia): When taken alone or with non-insulin diabetes medications, Januvia has a low risk of causing hypoglycemia (low blood sugar), making it safer for many people with type 2 diabetes.
  4. Convenient Dosing: Januvia is taken once daily, which makes it a convenient option for people who need a consistent way to manage their blood sugar.
  5. Can Be Combined with Other Medications: Januvia can be used alongside other diabetes medications, such as metformin, thiazolidinediones, or insulin, making it a flexible part of a comprehensive diabetes management plan.

Side Effects

Like all medications, Januvia can cause side effects, although not everyone will experience them. The most common side effects include:

  • Headache
  • Sore throat
  • Upper respiratory tract infection (cold-like symptoms)
  • Nausea or stomach discomfort

Although rare, more serious side effects may occur, including:

  1. Pancreatitis (inflammation of the pancreas): Symptoms may include persistent severe abdominal pain, nausea, and vomiting. If you experience these symptoms, seek medical attention immediately.
  2. Allergic Reactions: Some people may experience signs of a serious allergic reaction, including swelling of the face, lips, tongue, or throat, and difficulty breathing. If you notice these symptoms, get medical help immediately.
  3. Kidney Problems: Januvia can affect kidney function, especially in people with preexisting kidney disease. Kidney function should be monitored during treatment.
  4. Joint Pain: Some people may experience severe joint pain while taking Januvia. If you have persistent or severe joint pain, consult your healthcare provider.
  5. Risk of Infections: Januvia may increase the risk of certain infections, such as urinary tract infections or upper respiratory infections.

How to Take Januvia (Sitagliptin) 50mg Tablets

  1. Dosage: The typical dose of Januvia (Sitagliptin) is 50mg once daily. However, your doctor may adjust the dosage depending on your needs and any other medications you may be taking.
  2. When to Take: Januvia can be taken with or without food. To help you remember, take it at the same time every day.
  3. Missed Dose: If you miss a dose of Januvia, take it as soon as you remember unless it is almost time for your next dose. Do not take two doses simultaneously to make up for a missed dose.
  4. Storage: Store Januvia at room temperature, away from moisture and heat. Keep it out of reach of children.

Recommendations for Use

  • Regular Monitoring: Monitoring your blood sugar levels while taking Januvia is important to ensure it works as expected. Your doctor may adjust the dose based on your blood sugar readings.
  • Diet and Exercise: Januvia works best with a healthy diet and regular physical activity. Follow your doctor’s recommendations for lifestyle changes that support blood sugar management.
  • Kidney Function: If you have kidney problems, your doctor may need to adjust your dosage or monitor your kidney function more frequently.
  • Hydration: Stay well-hydrated, as dehydration can affect blood sugar control and kidney function.

Frequently Asked Questions (FAQs)

Can Januvia cause low blood sugar (hypoglycemia)?
Januvia, when used alone, generally does not cause hypoglycemia. However, when taken in combination with other medications like insulin or sulfonylureas, the risk of low blood sugar may increase. Monitor your blood sugar regularly and adjust your medicines as your doctor advises.

Can I take Januvia if I have kidney problems?
Januvia may not be suitable for people with severe kidney problems. Your doctor will assess your kidney function and may adjust your dose if you have kidney disease.

Can Januvia be used for type 1 diabetes?
No, Januvia is not for the treatment of type 1 diabetes. It is specifically used for type 2 diabetes, in which the body produces some insulin but not enough to control blood sugar levels.

How long does it take to deliver Januvia tablets to the US?

International shipping of tablets to the US takes approximately 14 to 25 days. For domestic shipping, the estimated delivery time is up to 10 days.

Do I need a prescription to buy Januvia tablets?

While we offer the option to buy tablets without a prescription internationally, we strongly recommend consulting your physician and seeking medical advice before taking any medication.

Important Note:

Purchasing Januvia (Sitagliptin) 50mg Tablets online from USA-Pharmacy is simple and secure for US customers. It accepts trusted payment methods like Visa, Mastercard, and PayPal, which protect transactions and keep information safe. Customers benefit from guaranteed delivery, with a full refund offered if orders do not arrive as expected, fostering trust in online medication purchases. Responsive customer support is available via email at [email protected], typically responding within 48 hours to any medication or order status questions.

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