Active Ingredients
The active ingredient in Eldepryl is selegiline hydrochloride. An enzyme called monoamine oxidase B (MAO-B) breaks down dopamine in the brain. Selegiline selectively blocks this enzyme. By stopping MAO-B from working, Eldepryl helps keep dopamine levels steady. This lowers Parkinson’s disease symptoms like tremors, stiffness, and bradykinesia (slow movement).
How Eldepryl (Zelapar) Works
Eldepryl works by blocking the action of the enzyme monoamine oxidase B (MAO-B). MAO-B breaks down dopamine in the brain, a neurotransmitter that is essential for controlling movement and motor coordination. Parkinson’s disease damages dopamine-producing neurons in the brain, resulting in a decrease in dopamine levels. By inhibiting MAO-B, Eldepryl helps to slow the breakdown of dopamine, making it more available for use by the brain. This mechanism of action helps reduce the motor symptoms of Parkinson’s disease.
In addition, Eldepryl may also have an antidepressant effect, as it can increase the levels of other neurotransmitters like serotonin and norepinephrine. However, this effect is typically secondary to its role in treating Parkinson’s disease.
Uses
Doctors typically prescribe Eldepryl for the following medical conditions:
- Parkinson’s Disease: Eldepryl, especially when combined with levodopa, aids in managing the symptoms of Parkinson’s disease. It can help improve motor function, reduce tremors, and slow the progression of the disease.
- Depression: Although not the first-line treatment for depression, Eldepryl may be used when other antidepressants have not been effective. It helps increase dopamine and other neurotransmitter levels, which can improve mood and emotional well-being.
- Adjunctive Treatment with Levodopa: Eldepryl may make levodopa work better for people who are already taking it for Parkinson’s disease. This could lower motor fluctuations and make managing symptoms better overall.
Benefits
- Improvement in Parkinson’s Symptoms: Eldepryl helps reduce the symptoms of Parkinson’s disease, such as tremors, rigidity, and bradykinesia. It allows patients to have better control over their motor functions and may improve their quality of life.
- Adjunctive Treatment: When used with levodopa, Eldepryl can help increase the effectiveness of levodopa and reduce the “wearing-off” phenomenon that occurs when levodopa’s effects begin to fade.
- Potential Antidepressant Effects: For those who have Parkinson’s disease and also suffer from depression, Eldepryl can help by increasing the levels of dopamine, serotonin, and norepinephrine in the brain, improving mood and emotional health.
- Slow Disease Progression: Some studies suggest that Eldepryl may slow the progression of Parkinson’s disease by protecting dopamine-producing neurons in the brain.
Side Effects
Like all medications, Eldepryl can cause side effects. Some of the common and serious side effects include:
Common Side Effects:
- Nausea: A mild but common side effect.
- Dizziness or Lightheadedness: Especially when standing up quickly.
- Dry Mouth: Can cause discomfort, but may be manageable.
- Sleep Problems: Difficulty sleeping, insomnia, or unusual dreams.
Recommendations for Use & Safety Precautions
- Food Interactions: Avoid consuming foods high in tyramine (aged cheese, cured meats, soy products, etc.), as it may lead to a dangerous increase in blood pressure.
- Combination with Other Medications: Always inform your healthcare provider about any other medications you are taking, especially antidepressants, blood thinners, and other MAO inhibitors, to avoid interactions.
- Blood Pressure Monitoring: It’s important to regularly monitor your blood pressure, particularly at the start of your treatment, to catch any increases Eldepryl might be causing.
- Alcohol: Limit or avoid alcohol consumption while taking Eldepryl, as alcohol can increase the risk of side effects like dizziness and drowsiness.
- Pregnancy & Breastfeeding: Eldepryl should only be used during pregnancy if clearly needed, and it is not recommended while breastfeeding. Consult your doctor for more information.
- Avoid Abrupt Discontinuation: Do not stop taking Eldepryl suddenly, as this may cause withdrawal symptoms or worsen Parkinson’s signs.
Frequently Asked Questions (FAQs)
Can Eldepryl cure Parkinson’s disease?
No, Eldepryl does not cure Parkinson’s disease but helps manage its symptoms and can slow the disease’s progression when used correctly.
How long does it take for Eldepryl to work?
Most patients begin to notice improvements in their symptoms within a few weeks of starting Eldepryl, but the full effect may take longer.
Is Eldepryl compatible with other Parkinson’s medications?
Yes, to increase the overall effectiveness of treatment, people frequently combine Eldepryl with levodopa or other Parkinson’s medications.
Is Eldepryl safe for elderly patients?
Eldepryl can be used in elderly patients, but careful monitoring for side effects is necessary, as older adults may be more sensitive to certain medications.
Can I take Eldepryl if I am on antidepressants?
Eldepryl may interact with certain antidepressants. It is important to inform your doctor if you are taking other medications, especially selective serotonin reuptake inhibitors (SSRIs) or other MAO inhibitors.
Does Eldepryl help with depression in Parkinson’s patients?
Yes, Eldepryl may have a mild antidepressant effect, especially in patients with both Parkinson’s disease and depression.
How long does it take to deliver Eldepryl to the US?
International shipping of tablets to the US takes approximately 14 to 25 days. For domestic shipping, the estimated delivery time is up to 10 days.
Do I need a prescription to buy Eldepryl?
While we offer the option to buy tablets without a prescription internationally, we strongly recommend consulting your physician and seeking medical advice before taking any medication.
Important Note:
Purchasing Eldepryl (Zelapar) online from USA-Pharmacy is simple and secure for US customers. It accepts trusted payment methods like Visa, Mastercard, and PayPal, which protect transactions and keep information safe. Customers benefit from guaranteed delivery, with a full refund offered if orders do not arrive as expected, fostering trust in online medication purchases. Responsive customer support is available via email at [email protected], typically responding within 48 hours to any medication or order status question.
